Agiomix BRCA panel uses the Next Generation Sequencing method to find out the mutations in the associated genes. The test results enable clinicians to identify a mutation in BRCA panel genes indicating a potential risk of development of Breast cancer.

OncoSeq® BRCA 

Under OncoSeq® Breast, screening is done for the below 15 genes to identify the cause of the disease:

ATM, BARD1, BRCA1, BRCA2, BRIP1, CDH1, CHEK2, MUTYH, NBN, PALB2, PTEN, RAD50, RAD51C, RAD51D, TP53.

OncoSeq® Colon

Under OncoSeq® Colon, screening is done for the below 10 genes to identify the cause of the disease:

APC, EPCAM, MLH1, MSH2, MSH6, MUTYH, PMS2, PTEN, STK11, TP53

OncoSeq® Repair

Under OncoSeq® Repair, screening is done for the below 14 genes to identify the cause of the disease:

ATM, BARD1, BRCA1, BRCA2, BRIP1, CHEK2, NBN, PALB2, RAD51C, RAD51D, MLH1, MSH2, MSH6, PMS2 (Does not include MRE11A)

OncoSeq® Guard

Under OncoSeq® Guard, screening is done for the below 2 genes to identify the cause of the disease:

TP53, CHEK2

Who should get OncoSeq® Breast Screening done?

  • An individual who is diagnosed with the cancer
  • When there is a family history of cancer
  • When there is an increased risk of cancer
  • When you are worried about the risk of cancer

 

Sample Requirement

  • DNA in TE Buffer or Water
  • Peripheral Blood in EDTA Tubes

 

Relevant Syndromes Covered:

Hereditary Breast and Ovarian Cancer Syndrome, Li-Fraumeni Syndrome, Cowden (PTEN) Hamartomas Syndrome, Peutz-Jeghers Syndrome, Hereditary Diffuse Gastric Cancer Syndrome

For more details about each panel and a complete list of syndromes, please contact us at 800 – GENOMICS (43666427)