Viruses constantly change through mutation, creating new variants. So far, multiple variants of the Covid-19 virus have been documented globally. These changes should be monitored by scientists, including changes to the spikes on the surface of the virus. By carefully studying viruses, scientists can learn how the changes might affect how it spreads and how sick people will get from it. Whole genome sequencing is a critical tool in understanding emerging viruses.
Next-Generation Sequencing (NGS) can track COVID-19 transmission and viral mutations, enforce testing protocols and infection control measures, and guide vaccine and therapeutic development.
Viral mutations can impact:
- Vaccine efficacy
- Transmission rates
- Disease severity
- Accurate viral detection
- Increased false-negative rates for COVID-19 testing
Here at Agiomix we have adopted a workflow of full Covid-19 virus genome sequencing for detection, research, and surveillance, with a customised panel that allows for more robust and confident variant calling, even when the virus mutates over time.